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Toxicol Sci 2004;82:374–80 [DOI] [PubMed] [Google Scholar] 83.Wolf KK, Wood SG, Hunt JA, Walton-Strong BW, Yasuda K, Lan L, Duan SX, Hao Q, Wrighton SA, Jeffery EH, Evans RM, Szakacs JG, von Moltke LL, Greenblatt DJ, Court MH, Schuetz EG, Sinclair PR, Sinclair JF

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Although this pathogen lacks catalase, which is common in prokaryotic and eukaryotic cells to combat oxidative stress, the pneumococcus relies on a unique set of proteins to manage its oxidative stress response (OSR)[3], an specialized mechanism allow it to tolerate oxidative stress and thrive in these diverse oxygen environments