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We order vitamin B12 and folate testing when a person with Down syndrome we are evaluating has symptoms described above, has a lab abnormality for which follow up testing of vitamin B12 and/or folate is indicated, or the person has a condition in which deficiency is common (e.g., celiac disease)
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In fact, recent data showed that different Bifidobacterium strains have complementary pathways for utilizing the prebiotics inulin-type fructans and arabinoxylan oligosaccharides (AXOS) (Rivière et al., 2018)