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GABA supplements improve relaxation, so researchers combined GABA with niacin (vitamin B3) which can cross the blood brain barrier- this allows Picamilon to increase GABA in the brain and provide the calming and anxiolytic (anti-anxiety) benefits

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Collectively, this study provides a solid foundation for future exploration into the impact of NNMTi-and diet-mediated changes to the gut microbiome in obese and lean populations, as well as future targets to investigate mechanistically with NNMTi treatment