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Experimental evidence indicates that AS-IV downregulates advanced glycation end product (AGE) expression in hippocampal tissue in aging model rats, thereby inhibiting AGE-RAGE protein interactions on neurons and inflammatory cells, suppressing NF-κB pathway activation, and reducing inflammation-related factors such as IL-6, IL-1β, and TNF-α
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However, as with any medical treatment, it should be administered under the supervision of qualified healthcare professionals