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A 2023 pharmaceutical review pointed out that BPC-157 increases expression of VEGFR2, a key receptor for vascular growth, in animal models

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(Dali-Youcef and Andrès, 2009) Other people at risk include those who have had intestinal surgeries, or have chronic conditions which affect the gut , such as Crohn’s disease or celiac disease (Dahele and Ghosh, 2001)