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What it is for B12 injections are prescribed for the treatment of many illnesses like: Pernicious anemia Vitamin B12 deficiency Intense nerve pain or inflammation Intense muscular pain Sciatica Lumbar osteoarthritis Arthritis Diabetic neuropathy Vitamin B12 injections can also be prescribed in some cases of a herniated disc or narrowing of the spinal cord near the neck, especially when the pain starts in the neck and radiates to an arm