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Autosomal dominant gain-of-function mutations such as those in STAT1 (signal transducer and activator of transcription 1) can also lead to inhibition of Th17 development, and increased susceptibility to CMC [325, 326]

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Note: If you experience a severe allergic reaction after taking any supplement—such as swelling of the lips, face, or tongue, difficulty breathing, wheezing, or widespread hives—call 911 or go to the nearest emergency room immediately